Skin Active Cellular Restoration

For firmer, lifted, less wrinkled, younger look

Formulated to synergistically restore skin’s essential cells, rebuild the deep skin layers of collagen, hyaluronic acid and elastin and reduce damage due to free radicals for skin that is firmer, more lifted, less wrinkled and vibrant. It also protects the skin and prevents ageing. Particularly beneficial for sagging, damaged, aged skin.

This unique multi-task formulation contains many high potent ingredients that function synergistically to provide multiple benefits including Alpha and Poly Hydroxy Acids, Peptides, Apple Stem cell extract, Broad Spectrum Antioxidant Complex.

Cellular Restoration is part of the Skin Active line of products, which also include Exfoliating Wash, Matrix Support SPF20 and Intensive Eye Therapy. This is a high strength regimen for over 35 years of age with tolerant skin.

Fragrance-Free. Paraben-Free. PABA-Free. Non-comedogenic, Non-acnegenic. Not tested on animals.

Size: 50 g

This potent cream takes a multi-mechanistic approach to rejuvenating cellular function and strengthening skin’s underlying structure with collagen, elastin and hyaluronic acid. This unique multi-task formulation of state of the art ingredients contains Apple Stem Cell Extract which protects and extends the life of skin’s own stem cells, helping to delay the effects of aging. Peptides enhance new collagen production  and reduce the appearance of deep wrinkles. Glycolic Acid is clinically proven to increase collagen production and hyaluronic acid, plumping and filling the skin so that wrinkles are smoothed from the inside out.

A powerful combination of the antioxidants Maltobionic Acid and Gluconolactone helps stimulate repair in  the deep skin layers, limit damage due to oxidation and neutralise free radicals to prevent the breakdown of collagen and elastin. In addition, grape seed extract, a polyphenol antioxidant known for its anti-inflammatory properties, works with SuperFruit antioxidant extracts of pomegranate, blueberry, and acai to protect against cell aging from daily environmental stressors.


Apply to the face and neck at night following cleansing and any other treatment products. A light peeling or tingling sensation may occur when using this high strength formulation. If uncomfortable, reduce usage to every other day until skin adjusts. Sensitive skin: Use every other day for 2 weeks, then once a day thereafter.

Note: Cellular Restoration (retail size) is packaged in an airless tube to ensure product stability. The tube will flatten as product is dispensed to maintain an airless environment.


SYNERG FORMULA 15.0 - High Strength Blend of Polyhydroxy Acid (PHA), Alpha Hydroxy Acid (AHA) and Bionic PHA - (5% Gluconolactone + 5% Glycolic Acid + 5% Maltobionic Acid) 

Helps repair and strengthen skin

  • PHAs and AHAs enhance skin renewal (cellular turnover and exfoliation), resulting in noticeably smoother skin and brighter, more even skin tone
  • PHAs and AHAs plump skin (increase skin own hyaluronic acid) resulting in fuller, younger looking skin with visibly fewer lines and wrinkles
  • PHAs attract and hold water, and strengthen the skin’s barrier so that it is less susceptible to irritation and environmental stress

Glycolic Acid stimulates the cells that produce collagen, hyaluronic acid and elastin (elastic fibers), reducing the appearance of sagging and wrinkles

  • Increased collagen strengthens skin for firmness and lift 
  • Increased hyaluronic acid plumps and fills the skin for fewer visible wrinkles 
  • Stronger elastin gives skin a youthful resiliency 

Helps Prevent Aging

  • PHAs have antioxidant properties, which help prevent cell damage
  • Gluconolactone and Maltobionic Acid inhibit the naturally occurring enzymes (MMPs) that degrade collagen and      elastin, preserving the skin’s deep matrix (structure) and reducing the appearance of sagging and wrinkling

Hydrates skin

  • PHA’s high water-attracting properties provide superior hydration– the foundation of healthy skin
  • Maltobionic Acid forms a  hydra-film, which delivers moisture, making skin feel softer and smoother in minutes and providing long lasting hydration



Strengthen skin and reinforces firmness and tone for a more lifted and contoured appearance

  • Peptides serve as cellular messengers to stimulate new collagen, restoring a more youthful look
  • Stimulate the natural process of skins's deep layer restoration, building the skin’s structure for a smoother, more lifted look


APPLE STEM CELL EXTRACT (Derived from rare Swiss Uttwiler Spätlauber Apples)

Protects and maintains the function of human skin stem cells, preserving the skin’s youthfulness and vitality

  • Delays cellular aging (biological aging)



Provides antioxidant protection and prevents ageing

  • Helps guard skin cells against aging oxidative damage by protecting against the formation of free radicals and  neutralizing existing free radicals. This proprietary antioxidant blend inhibits the breakdown of elastin and prevents oxidation to help protect the skin’s structure:


-Maltobionic Acid

-Chardonnay Grape Seed Extract is a potent antioxidant, 36% more effective than Vit C and 85% more effective than Vit E

-Antioxidant Berry Extract Blend (chardonnay grape seed, pomegranate,blueberry,acai)

-Vitamin E (0.5%) provides both antioxidant protection and skin conditioning



Conditions and softens skin


Neostrata Skin Active Cellular Restoration is formulated to rebuild the deep skin matrix for skin that is firmer and more lifted.  Participants (shown as %) noted these benefits after 4 weeks of twice daily application:

  • 100% good spreadability
  • 97% smoother texture
  • 97% improves overall appearance
  • 97% has a nice feel upon application
  • 97% gentle, non-irritating
  • 97% improvement in overall appearance
  • 94% nice consistency/thickness
  • 94% easily absorbed
  • 88% hydrates all day
  • 88% is compatible with makeup
  • 85% skin looked younger
  • 82% overall signs of aging are less noticeable
  • 82% skin feels hydrated without feeling greasy
  • 79% skin is brighter, more luminous
  • 76% more even skin tone/color
  • 73% skin improved immediately upon application
  • 73% fades age spots
  • 73% reduces pore size
  • 73% increased firmness/elasticity
  • 70% fine lines are less noticeable
  • 70% wrinkles are less noticeable
  • 70% more youthful skin, fuller/plumper skin 


About this Brand

Discover the dermatology developed skin care collections recommended and highly regarded by skin care experts around the world. NeoStrata Company, Inc., located in Princeton NJ, develops and ...